AIMS LEAP Timepoint 1 (T1) and Timepoint 2 (T2)
ELU-4-4D20BB-1
The Longitudinal European Autism Project (LEAP) is currently the largest study in the world to identify variability in autism in terms of behaviour, cognition, co-occurring conditions, outcomes, brain structure/function and genetics. AIMS-LEAP participants have been followed up longitudinally over time, with the current dataset including Timepoint 1 and Timepoint 2 (approx. 12-24-months apart).
- Project Title
- AIMS Longitudinal European Autism Project
- Project website
- https://www.aims-2-trials.eu/leap-front-page/
- Longitudinal European Autism Project (LEAP) - DTI - Time point 1 & 2
- Longitudinal European Autism Project (LEAP) - Resting-state fMRI - Timepoint 1 (and 2)
- Longitudinal European Autism Project (LEAP) - Task based fMRI - Timepoint 1 (and 2)
- Longitudinal European Autism Project (LEAP) - Genetics
- Longitudinal European Autism Project (LEAP) - Structural MRI - Time point 1
- Longitudinal European Autism Project (LEAP) - Clinical - Time point 1 & 2
- Longitudinal European Autism Project (LEAP) - Cognitive - Time point 1 & 2
- Longitudinal European Autism Project (LEAP) - Eyes Tracking - Time point 1 & 2
- Longitudinal European Autism Project (LEAP) - EEG- Time point 1 & 2
- Primary Purpose
- Autism Innovative Medicines Studies - Longitudinal European Autism Project (AIMS - LEAP)
- Study Types
-
C71104
- Description of Cohorts
- 437 autistic individuals and 300 non-autistic individuals total. Please note that N for individual datasets available here will be lower, and will differ between data modalities, due to participant consent preferences for external sharing and data quality. Total number 734 can vary depending on the study measure and timepoint, as well as participant consent preferences for external data sharing
- Informed Consent Given?
- True
- Multi-center Study?
- True
- Organisms
- Homo sapiens
- Number of subjects
- 737
- Diseases
- Intellectual disability Autism
- Sample Sources
- Neuroimaging Data derived from blood and saliva samples Eye-tracking Clinical Cognitive
- Type of Samples Collected
- Eye tracking Saliva Whole blood tempus Whole blood EDTA Cognitive Task based functional magnetic resonance imaging Physiological Psychometrics Structural magnetic resonance imaging Electroencephalography Questionnaires Diffusion Tensor Imaging Blood plasma Resting state functional magnetic resonance imaging Interviews
- Cohort characteristics
-
6-35 year