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203 studies found
Expression data from human skin biposies (lesional a...
Comparative RNA expression profiles from uninvolved and lesional skin of 13 patients with mild to severe plaque-type psoriasis.
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Expression data from human with lupus nephritis (LN)
RNA from glomeruli and tubulointerstitial compartments was extracted and processed for hybridization on Affymetrix microarrays.
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Expression data from intestinal mucosa of patients with UC
Ulcerative colitis patients and non-inflammatory controls were collected for RNA extraction and hybridization on Affymetrix microarrays. Inclusion criteria for UC patients were: age between 18 and 65, diagnosis of UC established at least 6 months before inclusion and exclusion of concomitant infection. Active disease was defined by endoscopic and histologic score: Mayo sub score >=2 and MATTS >=3 respectively . Inactive disease was also defined by endoscopic and histologic score: Mayo sub sco...
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Expression data from peripheral blood - blood draws...
Blood was collected immediately prior to, and two hours after challengeThe change in gene expression (post expression minus pre expression) in ERs was compared with the change in gene expression in DRs using age and sex as covariatesPreprocessing and probeset filtering were applied to the entire dataset (28 CEL files) using the Factor Analysis for Robust MicroArray Summarization (farms) package in RThe Linear Models for MicroArrays (limma) package was used to determine differential gene expre...
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Expression data from primary human keratinocytes exp...
Primary keratinocytes from three donors (subjects 1, 2, and 3) were obtained and were either untreated (control) or exposed to cytokines (IL-4, IL-13, IFN-alpha, IFN-gamma and TNF). For the IL17A samples, primary keratinocytes were obtained from six donors, with cells derived from three donors treated with IL-17A and cells derived from the other three donors left untreated (i.e., unpaired control samples).
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Expression data from skin biopsy samples from patien...
Skin biopsy samples (n=170) were collected at baseline for RNA extraction and microarray analysis from 85 patients with moderate-to-severe psoriasis without receiving active psoriasis therapy. The sample title is concatenated as <sample collection site ID>_<subject ID>_<skin type>.
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Expression data of substantia nigra from postmortem ...
Substantia nigra tissue from postmortem brain of normal and Parkinson disease patients were used for RNA extraction and hybridization on Affymetrix microarrays: 9 replicates for the controls and 16 replicates for the Parkinson's disease patients were used. Both cohorts included males and females.
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Expression data of synovial cells isolated from pati...
We isolated synovial cell culture from patients with rheumatoid arthritis and osteoarthritis. Fibroblast from patient with osteoarthritis was used for the reference.
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