Data Catalog

Expression data from peripheral blood - blood draws...

Blood was collected immediately prior to, and two hours after challengeThe change in gene expression (post expression minus pre expression) in ERs was compared with the change in gene expression in DRs using age and sex as covariatesPreprocessing and probeset filtering were applied to the entire dataset (28 CEL files) using the Factor Analysis for Robust MicroArray Summarization (farms) package in RThe Linear Models for MicroArrays (limma) package was used to determine differential gene expre...

Upper airway gene expression is an effective surroga...

Upper airway (nasal) and lower airway (bronchial) epithelial brushings obtained from a cohort of 54 allergic asthmatics and 30 matched healthy controls were profiled by gene expression by microarray. Subjects were assayed for gene expression, serum total IgE, blood eosinophils and serum periostin.

Nasal scrape gene expression profiling in asthmatics

Nasal scrape samples were collected from asthmatics and healthy controls and subjected to expression profiling using Affymetrix HG-U133Plus2.0 microarrays.

Sputum gene expression profiling in asthmatics

Sputum samples were collected from asthmatics and healthy controls and subjected to expression profiling using Affymetrix HG-U133Plus2.0 microarrays.

Human rhinovirus infection causes different DNA meth...

Bisulphite converted DNA from matched mock and human rhinovirus-16 infected nasal epithelial cells from Healthy (n=3) and Asthmatics (n=6) adults were hybridized to the Illumina DNA methylation 450K Bead Array.

Airway epithelial gene expression in asthma versus h...

Gene expression comparisons were made between: 1. asthmatics and healthy controls, and 2. Th2 high asthma and Th2 Low asthma/Healthy controls. The gene expression alterations most associated with asthma were then used in gene set enrichment analyses and gene signature development to compare this asthma dataset to COPD gene expression datasets.