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24 studies found

asthma

Isolated fresh bronchial epithelial cells were placed into trizol for further analysis.

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Short-term exposure to diesel exhaust is associated ...

This cohort consist of genomic DNA extracted from 16 individuals under 6 distinct conditions, bisulphite converted and hybridized to the Illumina Infinium HumanMethylation450 Beadchip for genome wide DNA methylation profiling.

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Expression data from asthmatic and healthy airway s...

Asthmatic airway smooth muscle cells (ASMC) are intrinsically different and have a differential transcriptional response to pro-fibrotic, pro-proliferation and pro-inflammatory stimuli than ASMC from healthy patients. We sought to identify genes that are differentially expressed between asthmatic and healthy ASMC under various stimulations which mimic the asthmatic airways. To this end, we obtained human ASMC from bronchial biopsies and explanted lungs from doctor diagnosed asthmatic patients...

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Characteristic DNA methylation profiles in periphera...

Peripheral blood was collected from adults with eosinophilic asthma (EA; n=21), paucigranulocytic asthma (PGA; n=22), neutrophilic asthma (NA; n=9), and healthy controls (n =10). Blood monocytes were isolated using ficoll density gradient and immuno-magnetic cell separation. Bisulfite converted genomic DNA was hybridised to Illumina Infinium Methylation27 arrays, and analysed for differential methylation using R/Bioconductor packages

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Gene expression changes in blood RNA after swimming ...

Expression profile differences were determined between total RNA extracted before and after exposure to trihalomethanes present in swimming pool water for 40 minute from whole blood samples from 33 healthy human individuals.

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The Nasal Methylome and Childhood Atopic Asthma

Case control design with nasal epithelial cells from 36 atopic asthmatic and 36 nonatopic nonasthmatic children from the inner cityNote: The Sample data tables are incomplete (truncated at 65535 rows, related to row-limit in older version of Excel).

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Comparison of mRNA expression in circulating T-cells...

mRNA samples were collected from circulating CD4+ and CD8+ T-cells from healthy donors as well as donors with severe and non-severe asthma.

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