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235 studies found
Gene expression profiling in psoriatic lesional and ...
From each of the 25 psoriasis patients, we obtained two pre-dose biopsies, one from a lesion and the other from non-lesional skin in the same general body geography, and two post-dose biopsies. Total RNA was extracted from 6mm punch biopsies that were split in half. A total of 99 samples were run on Affymetrix HU133 Plus 2.0 microarrays. There was no paired non-lesional sample for 'T_lesional_pre-dose' (skn55789).
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Gene expression profiling of human monocytes and mon...
Blood samples were obtained from 86 patients with symptoms of acute coronary syndrome who had undergone coronary angiography at the department of cardiology of the Pitié-Salpêtrière Hospital, Paris and who had on stenosis > 50 % diagnosed in at least one major coronary artery.48 monocyte and 48 macrophage samples (38 pools of 2 samples and 10 individual samples for each type of RNA) were hybridized to the RNG/MRC platform.
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Gene expression profiling of parkinsonian substantia nigra
Post-mortem human brains were obtained from moderately to severe parkinsonism individuals based on the Hoehn & Yahr criteria. All the subjects were negative for AD pathology according to Braak & Braak. The average age for PD and control is 76.6 and 77.8 years, respectively. The average postmortem delay for PD and control is 26.2 and 19.8 hours, respectively.
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Genome-Wide Profiling of Airway Epithelial Cells in ...
1) Comparison of gene expression in asthmatics to healthy controls2) Comparison of smokers to healthy controls3) Comparison of change in gene expression in the fluticasone treated group to the change in the placebo treated group
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Genome-wide analysis of Crohn's disease and ulcerati...
Total RNA obtained from intestinal biopsies were analyzed using whole-genome microarrays.
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Genome-wide analysis of atypical NK cell subset in m...
Isolated splenic NK1.1+ cells are compared between B6 WT and TLR7tg mice
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Genome-wide gene expression differences between Croh...
To identify pathogenic processes underlying these disease subtypes, using single endoscopic pinch biopsies, we elucidated gene expression patterns of active and inactive areas of UC and CD, and compared these to infectious colitis and healthy controls. An unsupervised classification of a total of 36 samples yielded promising separation between IBD affected, unaffected, non-IBD colitis and normal controls, suggesting distinctive gene expression patterns for each sample type. The Significance A...
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