Data Catalog

EUbOPEN wave 1

This submission holds the raw data and processed images for a high-content live-cell multiplex screen. The screen is used for chemogenomic compounnd annotation, i.e. the evaluation of e.g. cytotoxic effects. This submission is about a set of >550 chemogenomic candidate compounds, tested in a pre-screen and a primary screen. Further information about the EUbOPEN project, from which this set and experiment originated can be found in the links section.

Types: Compound Libraries And Screening Bioimaging Confocal Microscopy Brightfield Microscopy

Early and long-standing rheumatoid arthritis: molecu...

PBMC then RNA were extracted from synovial biopsies of 4 eraly RA patients, 4 long-standing RA patients and from 7 normal synovium used as control. Each sample was hybridized three times in different nylon membrane.

Efficacy of anti-TNF biologic agent, infliximab, for...

Forty-two and 26 consecutive RA patients followed at Saitama Medical Center, for retrospective and verification studies, respectively, who were resistant to standard MTX treatment, were enrolled. The serum CRP level was used for the definition of the level of inflammation of each patient, 0.3 mg/dl or less as “no inflammation” (NI), and more than 0.3 mg/dl as “residual inflammation” (RI) at 14 weeks after the first treatment with infliximab infusion. Differentially expressed genes between the...

Exon-array profiling of peripheral blood cells in th...

In this study, we used exon array profiling to investigate biomarker gene analyzing 49 patients samples (six time points) and 6 control samples. Whole-blood cell drawn from an antecubital vein at six time points following STEMI diagnosis. The first time (T0) was on patient admission to the Emergency Unit prior to receiving any medication. The second time (T2) blood collection occurred after successful mechanical reperfusion and stenting of the infarct artery within 2 h after T0. Collectio...

Expression Data from Macrophage Maturation and Polar...

Freshly isolated monocytes were cultured in the presence of M-CSF (100 ng/ml) for 7 days, and then activated. The study includes Monocytes at day 0, macrophages at day 3 and 7, Interferon Gamma and LPS treated macrophages and IL-4 treated macrophages.