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29 studies found

EUbOPEN wave 1

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This submission holds the raw data and processed images for a high-content live-cell multiplex screen. The screen is used for chemogenomic compounnd annotation, i.e. the evaluation of e.g. cytotoxic effects. This submission is about a set of >550 chemogenomic candidate compounds, tested in a pre-screen and a primary screen. Further information about the EUbOPEN project, from which this set and experiment originated can be found in the links section.

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OncoTrack

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OncoTrack attempts to address the core problems of drug-based cancer therapies: the low response rate of patients to their therapies, as well as its inevitable consequence, the low approval rates of oncology drugs. Only about 10% of cancer drug candidates entering clinical development are granted marketing authorization. Our program is based on two seminal developments: significant progress in our ability to analyze the molecular characteristics of individual tumors and patients (predominantl...

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