Data Catalog

Expression data of synovial cells isolated from pati...

We isolated synovial cell culture from patients with rheumatoid arthritis and osteoarthritis. Fibroblast from patient with osteoarthritis was used for the reference.

Gene Expression Analysis in Peripheral Blood of Pati...

The measurement of expression level of several genes shown below in peripheral blood of human subjects (18 patients with rheumatic disease) before and after tocilizumab medication using DNA microarray (Hitachi human oligo chip) was conducted in this test,1) Interleukin 6 (IL-6), membrane IL-6 receptor (IL-6R) and soluble type of the IL-6R,2) several cytochrome P450 as follows: CYP3A4, CYP2D6, CYP2C9, CYP2C19.Number of human subjects was 18 and peripheral blood samples drawn at 4 time points:d...

Gene expression in rheumatoid arthritis synovial macrophages

Macrophages from synovial fluids of five RA patients were isolated by ficoll density gradient centrifugation, followed by positive selection of CD14+ cells using magnetic beads. The patients’ diagnoses were determined by their physicians, in each case a Board-certified rheumatologist at the Hospital for Special Surgery, and were definite RA according to American College of Rheumatology criteria. De-identified samples were processed in an anonymous manner using a protocol approved by the Insti...

Human Rheumatoid Arthritis Synovial Fibroblasts: Con...

Two-condition experiment, BSA vs. Tenascin-C stimulated cells. One replicate per array.

Human bone marrow-derived mononuclear cells (BMMC): ...

Bone marrow was obtained from patients with RA (n=9) or OA (n=10). The bone marrow samples from the 10 OA patients are used as controls.

Identification of markers of responsiveness in rheum...

PBMC then RNA were extracted from blood samples of 7 anakinra responders, 7 anakinra non responders and 1 pool of healthy subjects used as control. Each sample was hybridized twice in different nylon membrane. The control sample was hybridized twice in each nylon membrane.

Immunity and Defense Genes in Peripheral Blood Monon...

33 samples analyzed corresponding to 18 Rheumatoid Arthritis Patients and 15 Controls

Key Regulatory Molecules of Cartilage Destruction in...

To reveal the RA-related chondrocyte gene expression profile, genome-wide microarray analysis of RASF stimulated human chondrocytes compared to NDSF stimulation was performed. Unstimulated chondrocytes were analyzed for baseline gene expression. For microarray analysis of RASF and NDSF stimulated and unstimulated chondrocytes, respectively, two RNA pools were analyzed, each pool consisting of equal amounts of RNA from three different donors.