Search studies

26 studies found

A global transcriptome analysis of keratinocytes upo...

expression profiling of primary human keratinocytes transfected with 10nM miR-31 hairpin inhibitor (anti-miR-31) or control hairpin RNA (anti-miR-Ctrl) for 48 hours (biological triplicates in each group) was performed using the Affymetrix GeneTitan system.

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A single intradermal injection of IFN-γ induces a ps...

RNA was isolated from whole skin punch biopsies of either healthy or non-lesional psoraisis patients at baseline or 24 hours after placebo or IFN-g injection.

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Activated T cell gene expression profile associated ...

T cells from PBMCs isolated from patients and healthy controls were in vitro activated with anti-CD3 and anti-CD28 for 72 hours. After T cell activation, cells were harvested and RNA extracted for microarray analysis.

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BIOMAP

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Aggregation of all BIOMAP cohorts

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Cytokine treated normal human epidermal keratinocytes

NHEK were treated with IL-19, IL20, IL-22, and IL24, with controls untreated, along with IL1b, IFN gamma, and KGF.

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Dominant Th1 and Minimal Th17 Skewing in Discoid Lup...

Comparison of transcriptomes between skin conditions

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Expression data for human epithelium from subjects w...

Gene expression profiling was performed on total RNA from nonlesional epidermal samples from 5 subjects with atopic dermatitis, 4 subjects withpsoriasis, and 5 nonatopic controls using the Illumina Sentrix HumanRef-8 Expression BeadChip. There were duplicate (technical replicate) arrays run for 2 of the nonatopic control samples (the normalized transformed expression values of replicate pairs were averaged before performing data analysis, also, for each probe, the combined value for replicat...

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Expression data from affected skin from psoriasis mo...

Expression patterns associated with mouse phenotypes were evaluated by comparing lesional skin from transgenic or IMQ-treated mice (n = 2-3) with normal skin obtained from control mice (n = 2-3).

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