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21 studies found
Time-dependent transcriptomic profiles of mouse hipp...
40 animals were in the study; 80 samples were analyzed via Illumina beadchip microarray, a total which included 2 samples (IL and CL hippocampus) from each animal. Of the 80 samples,the n were as follows: IL-KA-7d, 8; CL-KA-7d, 8; IL-KA-28d, 9; CL-KA-28d, 9; IL-KA-60d, 9; CL-KA-60d, 9; IL-sham-7d, 4; CL-sham-7d, 4; IL-sham-28d, 5; CL-sham-28d, 5; IL-KA-60d, 5; CL-KA-60d, 5.
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Transcriptional profiling of dentate granule cells i...
Each experimental group consists of 6 rats (biological replicates) from one laboratory at a single time point, except for the SSSE group (6 at day 1 after SSSE, 5 controls and at day 3 after SSSE, 4 at day 10). Thus granule cells were harvested from 164 rats.
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Whole transcriptome analysis of the hippocampus: tow...
We performed a genome wide analysis of genes differentially expressed during epileptogenesis. Virtually, all possible changes in the rat transcriptome were monitored at distinct time points corresponding to the latent to chronic phase transition of the pilocarpine model of epilepsy, which is probably the most extensively studied chemically inductive model of TLE. Genes identified as being differentially expressed were classified based on their respective biological functions to envisage proce...
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whole brains from nicotinic acetylcholine receptor s...
The experimental groups included six wild-type mice and five beta4-/- mice. All mice were 6-9 weeks old. Total RNA was extracted from whole brain tissue of the mice.
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