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5 projects found
AIMS Leap - AIMS Longitudinal European Autism Project
ELU-1-725846-1
The Longitudinal European Autism Project (LEAP) is currently the largest study in the world to identify variability in autism in terms of behaviour, cognition, co-occurring conditions, outcomes, brain structure/function and genetics.
Keywords: IMI projects Autism Neurodevelopment Accelerated longitudinal Neurodivergence Biomarkers Intellectual disability Cohort Observational Children Adolescents Adults
ImmUniverse
ELU-1-0A6EF9-1
Immuniverse research projects at LCSB aim at to better control and treatment of immune-mediated diseases by exploring the universe of microenvironment-imposed tissue signatures and their correlates in liquid biopsies. The precise aims of the ImmUniverse project are given below: Objective 1. Comprehensive molecular characterization of intestinal/dermal microenvironment and immune cell profiles that provides a data foundation for advanced bioinformatics, statistical and model-based analysis. ...
NCER-PD - National Centre of Excellence in Research for Parkin...
2b2ed412-b8ce-11f0-a3c4-0050569ae0bc
We currently do not know enough about Parkinson's disease. We are still far from understanding the relationship between the different symptoms and it is still a mystery why some people are affected and others not. In addition, the disease progression, whether it is slow or fast, cannot be predicted at the moment. As the causes of Parkinson's disease are still unknown, new research projects are necessary that give us new ways for prevention, diagnosis and treatment. The NCER-PD research team, ...
Keywords: Parkinson's disease neurological disorder Atypical Parkinson Cognitive data Imaging data Parkison's disease motor symptoms
MiBiPa - Non-invasive microbiome-derived multi-omic biomarker...
ELU-1-913FE2-1
Parkinson’s disease (PD) research benefits from knowledge of disease-specific risk and resilience factors and elucidation of pathophysiological concepts on the emergence of neurodegeneration. Presently the propagation of a-synuclein aggregation in PD is proposed to start in the periphery, i.e. in the enteric nervous system and the olfactory bulb. Aberrations within the gastrointestinal and nasal microbiomes may play a role in the initiation of this process. This is of particular relevance in...
Keywords: Parkinson’s disease microbiome biomarker
Test project - OncoTrack - Test project - Methods for systematic next generatio...
ELU-1-6CEACB-1
The goal of OncoTrack was to identify and characterize biological markers that will help our understanding of the variable make-up of tumours and how this affects the way patients respond to treatment. Cutting edge laboratory-based genome sequencing techniques coupled to novel computer modelling approaches were used to study both the biological heterogeneity of colon cancers (i.e. patient to patient variability) as well as tumour variation within the patient – for example, by comparing primar...