355 projects found
Collaboration for prevention and treatment of MDR bacterial infections
Keywords: IMI projects Antimicrobial resistance Infectious diseases AMR Accelerator Tools for predicting/monitoring efficacy Tools for predicting/monitoring safety Clinical trial design
Collaboration on the optimisation of macromolecular pharmaceutical access to cellular targets
Keywords: IMI projects Biologicals Drug delivery
COVID-19 infections - remote early detection
Keywords: IMI projects Respiratory diseases Infectious diseases Coronaviruses Diagnostics Digital health
A diagnostic test to improve surveillance and care of COVID-19 patients
Epigenetic changes including DNA methylation caused by environmental exposures may contribute to the heterogeneous inflammatory response in asthma. Here we investigate alterations in DNA methylation of purified blood monocytes that are associated with inflammatory phenotypes of asthma.
Keywords: NCBI GEO methylation profiling by array
This SuperSeries is composed of the SubSeries listed below.
Keywords: NCBI GEO expression profiling by array methylation profiling by array
Monocytes and T-cells play an important role in the development of atherosclerotic coronary artery disease (CAD). Differences in transcriptional activity of these cells might reflect the individual's atherosclerotic burden. Transcriptome analysis of circulating mononuclear cells from carefully matched atherosclerotic and control patients will potentially provide insights into the pathophysiology of atherosclerosis and supply biomarkers for diagnostic purposes. From patients undergoing coron...
Keywords: disease-state analysis macrophages expression profiling by array
The aim of this study was to investigate differential intestinal gene expression in patients with Crohn's disease (CD) and controls. 172 biopsies from CD and control subjects were studied. Endoscopic biopsies were taken at ileocolonoscopy from five specific anatomical locations including the terminal ileum for RNA extraction.
Keywords: NCBI GEO expression profiling by array