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Examples: APPROACH

375 projects found

VITAL

Vaccines and infectious diseases in the ageing population

Keywords: IMI projects Ageing-associated diseases Infectious diseases Vaccines Tools for predicting/monitoring efficacy Real-world data, evidence

353

VSV-EBOPLUS

Vaccine safety and immunogenicity signatures of human responses to VSV-ZEBOV

Keywords: IMI projects Infectious diseases Ebola and related diseases Vaccines Ebola+ Tools for predicting/monitoring efficacy

354

VSV-EBOVAC

Vaccine safety and immunogenicity signatures of human responses to VSV-ZEBOV

Keywords: IMI projects Infectious diseases Ebola and related diseases Vaccines Ebola+

355

WEB-RADR

Recognising Adverse Drug Reactions

Keywords: IMI projects Tools for predicting/monitoring efficacy Digital health Regulatory and HTA processes

356

WEB-RADR 2

WEB-RADR 2

Keywords: IMI projects Tools for predicting/monitoring safety Big data and knowledge management Real-world data, evidence Regulatory and HTA processes Methods for benefit/risk assessment

357

Whole blood transcript profiling of rheumatoid arthr...

The whole blood was collected pre-treatment from rheumatoid arthritis patients starting the anti_TNF therapy. All patients were naïve to anti_TNFs. The disease activity was measured using the DAS28 score at the pre-treatment visit1 (DAS28_v1) and 14 weeks after treatment visit3 (DAS28_v3). The response to the therapy was evaluated using the EULAR [European League Against Rheumatism] definition of the response. The objective of the data analysis was to identify gene expression coorelating wit...

Keywords: NCBI GEO expression profiling by array

358

Whole genome transcription and DNA methylation analy...

Our study has demonstrated that significant number of differential genes in SLE was involved in IFN, TLR signaling pathways and inflammatory cytokines. The enrichment of differential genes has been associated with aberrant DNA methylation, which may be relevant to the pathogenesis of SLE. Our observations laid the groundwork for further diagnostic and mechanistic studies of SLE and LN.

Keywords: NCBI GEO methylation profiling by genome tiling array

359

Whole transcriptome analysis of the hippocampus: tow...

Purpose: to evaluate changes in the transcriptome of hippocampal cells during the course of epileptogenesis, from the early events post status epilepticus (SE) to the onset of recurrent spontaneous seizures.Experimental Design: Gene expression profiling was analyzed in hippocampi of rats subjected to the pilocarpine model of epilepsy at different times during the course of epileptogenesis: 3 days post-SE (3D), 7 days post-SE (7D), and immediately (up to 12h) after the first spontaneous seizur...

Keywords: gene expression changes during epileptogenesis. expression profiling by array

360