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355 projects found
TransQST
Translational quantitative systems toxicology to improve the understanding of the safety of medicines
Keywords: IMI projects Tools for predicting/monitoring efficacy
313
Transcriptional Response of Human Microglial Cells t...
Microglial cells are resident macrophages in the central nervous system (CNS) and play a pivotal role in the innate and adaptive immune responses against microbial infections. The immune functions of microglia are regulated by a milieu of cytokines including interferon (IFN)-gamma. We here performed a series of experiments to acertain the transcriptional profile of human fetal microglial cells at 1, 6, and 24 h after IFN-gamma treatment. Primary human microglial cells were either untreated o...
Keywords: time-course microglia interferon-gamma macrophages expression profiling by array
314
Transcriptional analysis of left-sided colitis, panc...
This study characterizes the inflammatory processes in left-sided colitis, pancolitis, and UC-associated dysplasia at the transcriptional level in colonics biopsies in order to identify potential biomarkers and transcripts of importance for the carcinogenic behaviour of chronic inflammation
Keywords: NCBI GEO expression profiling by array
315
Transcriptional analysis of multiple brain regions i...
Transcriptional analysis of multiple brain regions in Parkinson's disease supports the involvement of specific protein processing, energy metabolism, and signaling pathways, and suggests novel disease mechanisms.This SuperSeries is composed of the SubSeries listed below.
Keywords: NCBI GEO expression profiling by array
316
Transcriptional analysis of prefrontal area 9 in Par...
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects
Keywords: NCBI GEO expression profiling by array
317
Transcriptional analysis of putamen in Parkinson's disease
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects
Keywords: NCBI GEO expression profiling by array
318
Transcriptional analysis of whole substantia nigra i...
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects
Keywords: NCBI GEO expression profiling by array
319
Transcriptional profiling of dentate granule cells i...
Global expression profiling of epileptogenesis has been confounded by variability across laboratories, epilepsy models, tissue sampled and experimental platforms, with the result that very few genes demonstrate consistent expression changes. The present study minimizes these confounds by combining Affymetrix microarray datasets from seven laboratories, using three status epilepticus (SE) models of epilepsy in rats (pilocarpine, kainate, self-sustained SE or SSSE) and the rat kindling model. ...
Keywords: NCBI GEO expression profiling by array
320
