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354 projects found

BD4BO

Big Data for Better Outcomes

Keywords: IMI projects Cardiovascular diseases Neurodegenerative diseases Cancer Alzheimer's disease BD4BO Patient involvement in R&D Big data and knowledge management Real-world data, evidence

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BEAT-DKD

Biomarker enterprise to attack DKD

Keywords: IMI projects Diabetes & metabolic disorders

26

BIOMAP

Biomarkers in atopic dermatitis and psoriasis

Keywords: IMI projects Autoimmune diseases Skin diseases Biobanks Disease taxonomy

27

BTCure

Be The Cure

Keywords: IMI projects Autoimmune diseases Tools for predicting/monitoring safety Disease taxonomy

28

BigData@Heart

Big data @ heart

Keywords: IMI projects Cardiovascular diseases BD4BO Big data and knowledge management Real-world data, evidence

29

BioVacSafe

Biomarkers for Enhanced Vaccine Immunosafety

Keywords: IMI projects Infectious diseases Vaccines Tools for predicting/monitoring efficacy

30

Blockade of interferon-γ normalizes IFN regulated ge...

Normal donor blood was incubated with or without IFN-g stimulation to establish an IFN-g gene signature. Systemic lupus erythematosus subjects were treated with placebo or AMG 811, a therapeutic anti-IFN--g antibody, and changes in the IFN--g signature in whole blood of these subjects was measured.

Keywords: NCBI GEO expression profiling by array

31

Bruton's Tyrosine Kinase Regulates TLR9 but not TLR7...

Plasmacytoid dendritic cells (pDCs) can be activated by the endosomal TLRs, and contribute to the pathogenesis of systemic lupus erythematosus (SLE) by producing type I IFNs. Thus, blocking TLR-mediated pDC activation may represent a useful approach for the treatment of SLE. In an attempt to identify a therapeutic target for blocking TLR signaling in pDCs, we investigated the contribution of Bruton's tyrosine kinase (Btk) to the activation of pDCs by TLR7 and TLR9 stimulation by using a selec...

Keywords: NCBI GEO expression profiling by array

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