Search projects
375 projects found
HARMONY PLUS
Healthcare alliance for resourceful medicines offensive against neoplasms in hematology – PLUS
Keywords: IMI projects Cancer BD4BO Big data and knowledge management Real-world data, evidence
169
HIPPOCRATES
Health initiatives in psoriasis and psoriatic arthritis consortium European states
Keywords: IMI projects Autoimmune diseases Skin diseases Biobanks Clinical networks Disease taxonomy Artificial intelligence
170
HT-project: Expression profiling after prolonged exp...
Febrile seizures are the most prevalent type of seizures among children up to 5 years of age (2-4% of Western-European children). Complex febrile seizures are associated with an increased risk to develop temporal lobe epilepsy. To investigate short- and long-term effects of experimental febrile seizures (eFS), we induced eFS in highly febrile convulsion-susceptible C57BL/6J mice at post-natal day 10 by exposure to hyperthermia (HT) and compared them to normotherm-exposed (NT) mice. We detecte...
Keywords: NCBI GEO expression profiling by array
171
Hippocampal gene expression signature following infl...
We used a systemic inflammatory challenge in animals with chronic mesial temporal lobe epilepsy to identify novel molecular pathways involved in seizure regulation. Mice were first rendered epileptic by a single intrahippocampal injection of kainic acid (KA). After a period of two-three weeks, mice developed spontaneous seizures and then received a single intraperitoneal injection of lipopolysaccharide (LPS) to mimic systemic inflammation, or saline as a control. Gene expression analysis by m...
Keywords: NCBI GEO expression profiling by array
172
Human Chronic Obstructive Pulmonary Disorder (COPD) ...
Chronic obstructive pulmonary disease (COPD) is an inflammatory lung disease with complex pathological features and largely unknown etiologies. Identification and validation of biomarkers for this disease could facilitate earlier diagnosis, appreciation of disease subtypes and/or determination of response to therapeutic intervention. To identify gene expression markers for COPD, we performed genome-wide expression profiling of lung tissue from 56 subjects using the Affymetrix U133 Plus 2.0 a...
Keywords: Disease state marker expression profiling by array
173
Human Rheumatoid Arthritis Synovial Fibroblasts: Con...
Transcriptional profiling of human rheumatoid arthritis synovial fibroblasts comparing control cells treated with BSA with cells treated with Tenascin-C.
Keywords: NCBI GEO expression profiling by array
174
Human bone marrow-derived mononuclear cells (BMMC): ...
Gene expression profiling of BMMC from patients with rheumatoid arthritis (RA) vs. osteoarthritis (OA).
Keywords: NCBI GEO expression profiling by array
175
Human colon expression in healthy controls, colon-on...
Colon gene expression in human IBD. The three major clinical subsets of Inflammatory Bowel Disease (IBD) include colon-only Crohn's Disease (CD), ileo-colonic CD, and Ulcerative Colitis (UC). These experiments tested differential colon gene expression in these three types of IBD, relative to healthy control samples, and the local degree of mucosal inflammation as measured by the CD Histological Index of Severity (CDHIS). Colon biopsy samples were obtained from IBD patients at diagnosis and d...
Keywords: Single time point in CD and UC and healthy controls. expression profiling by array
176
