Search projects

Gene expression analysis in absence epilepsy using a...

Objective:To identify genes involved in idiopathic absence epilepsies by analysing gene expression using a monozygotic (MZ) twin design.Methods:Genome-wide gene expression in lymphoblastoid cell lines was determined using microarrays derived from five discordant and four concordant MZ twin pairs with idiopathic absence epilepsies and five unaffected MZ twin pairs. Gene expression was analysed using three strategies: discordant MZ twins were compared as matched pairs, MZ twins concordant for ...

Keywords: Childhood Absence Epilepsy Juvenile Absence Epilepsy Idiopathic Generalised Epilepsy gene expression twin study monozygotic twins expression profiling by array

1