Search projects
142 projects found
Mapping of disease-associated expression polymorphi...
Analysis of expression quantitative trait loci (eQTLs) using RNA derived from freshly harvested peripheral blood CD4+ lymphocytes from 200 asthmatics collected in clinical settings.
Keywords: NCBI GEO expression profiling by array
89
Mechanisms Establishing TLR4-Responsive Activation S...
This SuperSeries is composed of the SubSeries listed below.
Keywords: NCBI GEO macrophages expression profiling by array genome binding/occupancy profiling by high throughput sequencing expression profiling by high throughput sequencing
90
Microarray predictor of response to infliximab in rh...
We sought to find a gene-expression multigene predictor of response to infliximab therapy in Rheumatoid Arthritis patients. Using internal and external cross-validation systems we have built and validated an 8-gene predictor for response to infliximab.
Keywords: NCBI GEO expression profiling by array
91
Molecular consequences of Csf1R (M-CSF receptor) inh...
Efficacy of Csf1R inhibition by PLX3397 compound in a mouse model of chronic epilepsy has been assessed by daily administration of either vehicle, 3 mg/kg or 30 mg/kg during 2 weeks monitoring. At the end of the study, RNA was extracted from study animals hippocampi to assess treatment consequences at the gene expression level in view of the in vivo efficacy results and the previously identified consequences of epilepsy in hyppocampus. Naive healthy mice were added separately to determine bas...
Keywords: NCBI GEO expression profiling by array
92
Molecular patterns in human ulcerative colitis and c...
Background & Aims. As a T cell-mediated disease of the colonic epithelium, ulcerative colitis (UC) is likely to share pathogenic elements with other T cell-mediated inflammatory diseases. Recently we showed T cell-mediated rejection of kidney and heart transplants share large scale molecular changes. We hypothesized that UC would manifest a similar disturbance, and that these features would correlate with response to infliximab. Results. UC biopsies manifested coordinate transcript changes ...
Keywords: NCBI GEO expression profiling by array
93
Mucosal expression profiling in (un)inflamed colon o...
This SuperSeries is composed of the SubSeries listed below.
Keywords: NCBI GEO expression profiling by array non-coding RNA profiling by array
94
Mucosal gene expression profiling in (un)inflamed co...
In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.
Keywords: NCBI GEO expression profiling by array
95
Mucosal miRNA expression profiling in (un)inflamed c...
In this study, we investigated if miRNA expression in UC mucosa is altered and correlated our findings with mucosal mRNA expression. Integration of mRNA and miRNA expression profiling may allow the identification of functional links between dysregulated miRNAs and their predicted target mRNA.
Keywords: NCBI GEO Non-coding RNA profiling by array
96
