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134 projects found
Expression analysis of dendritic cells, macrophages ...
Expression profiles at different time points during dendritic cell differentiation (induced by specific culture conditions) including monocytes as well as expression profiles between monocytes and completely differentiated cells (macrophages at day7 and dendritic cells at day7, respectively) were compared. Monocyte-derived dendritic cells (DC) were obtained by culturing elutriated monocytes with 20U/ml IL-4, 280U/ml GM-CSF and 10% FCS; monocyte-derived macrophages (MAC) were obtained by cult...
Keywords: NCBI GEO macrophages expression profiling by array
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Expression analysis of dissected GPi in Parkinson's disease
Genome-wide transcriptome analysis of expression changes in Globus Pallidus interna (GPi) from Parkinson's disease brain tissue versus control brain tissue.
Keywords: NCBI GEO expression profiling by array
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Expression analysis of laser-dissected SNpc neurons ...
Genome-wide transcriptome analysis of expression changes in laser-dissected SNpc neurons from Parkinson's disease brain tissue versus control brain tissue.
Keywords: NCBI GEO expression profiling by array
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Expression analysis of lymphoblast cells lines in Pa...
Genome-wide transcriptome analysis of expression changes in EBV transformed cell lines from the Coriell Cell Repository in Parkinson and Control subjects.
Keywords: NCBI GEO expression profiling by array
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Expression data for human epithelium from subjects w...
The expression and function of tight junction genes, in particular claudin-1, was studied in order to further understanding of the biology underlying atopic dermatitis.
Keywords: NCBI GEO expression profiling by array
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Expression data from advanced Parkinson's disease (P...
Sub-thalamic deep brain stimulation (DBS) reversibly modulates Parkinson’s disease (PD) motor symptoms, providing an unusual opportunity to compare leukocyte transcripts in the same subjects before and after neurosurgery and after disconnecting the stimulus (ON-and OFF-stimulus). Here, we report rapid stimulus-induced and largely reversible changes in PD leukocyte transcripts, which were larger in scope than the disease-induced changes. These transcript changes classified advanced pre- from p...
Keywords: NCBI GEO expression profiling by array
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Expression data from affected skin from psoriasis mo...
Development of a suitable mouse model would facilitate the investigation of pathomechanisms underlying human psoriasis and would also assist in development of therapeutic treatments. However, while many psoriasis mouse models have been proposed, no single model recapitulates all features of the human disease, and standardized validation criteria for psoriasis mouse models have not been widely applied. In this study, whole-genome transcriptional profiling is used to compare gene expression p...
Keywords: NCBI GEO expression profiling by array
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Expression data from airway epithelial cells from pa...
The link between upper and lower airways in patients with both asthma and allergic rhinitis is still poorly understood. As the biological complexity of these disorders can be captured by gene expression profiling we hypothesized that the clinical expression of rhinitis and/or asthma is related to differential gene expression between upper and lower airways epithelium.We used micro array to profile gene expression of primary nasal and bronchial epithelial cells from the same individuals and ex...
Keywords: NCBI GEO expression profiling by array
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