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Examples: APPROACH

185 projects found

Immune safety avatar: nonclinical mimicking of the i...

Certain treatments for cancers and autoimmune diseases work by altering the immune system. However, a major challenge for researchers is identifying potential efficacy and safety issues with these treatments early in drug development, before they are tested in humans. Part of the problem is that the tests used early in drug development do not reflect the full complexity of the human immune system. In addition, these tests tend to be based on a healthy immune system, which is different to the ...

Keywords: IMI projects Immunology Autoimmune diseases Tools for predicting/monitoring efficacy Tools for predicting/monitoring safety

89

Immune-Image

Specific imaging of immune cell dynamics using novel tracer strategies

Keywords: IMI projects Biologicals Imaging

90

Impentri

Development of Impentri, an intravenous imatinib formulation for COVID-19 acute respiratory distress syndrome (ARDS)

Keywords: IMI projects Respiratory diseases Infectious diseases Coronaviruses Conducting clinical trials

91

Inno4vac

Innovations to accelerate vaccine development and manufacture

Keywords: IMI projects IMI2 Vaccines Tools for predicting/monitoring efficacy Big data and knowledge management Artificial intelligence

92

K4DD

Kinetics for Drug Discovery

Keywords: IMI projects Tools for predicting/monitoring efficacy Tools for predicting/monitoring safety Drug discovery

93

KRONO

Evaluation of a production ready portable, point-of-need platform (instrument and reagents), direct from nasal swab test for the molecular diagnostic detection of COVID-19 infection

Keywords: IMI projects Respiratory diseases Infectious diseases Coronaviruses Diagnostics

94

LITMUS

Liver Investigation: Testing Marker Utility in Steatohepatitis

Keywords: IMI projects Diabetes & metabolic disorders Diagnostics Tools for predicting/monitoring efficacy Disease taxonomy

95

MACUSTAR

Intermediate AMD: development of novel clinical endpoints for clinical trials in patients with a regulatory and patient access intention

Keywords: IMI projects Ageing-associated diseases Eye diseases Tools for predicting/monitoring efficacy Patient involvement in R&D Imaging

96