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185 projects found
Expression analysis of lymphoblast cells lines in Pa...
Genome-wide transcriptome analysis of expression changes in EBV transformed cell lines from the Coriell Cell Repository in Parkinson and Control subjects.
Keywords: NCBI GEO expression profiling by array
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Transcriptional analysis of prefrontal area 9 in Par...
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects
Keywords: NCBI GEO expression profiling by array
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Expression analysis of dissected GPi in Parkinson's disease
Genome-wide transcriptome analysis of expression changes in Globus Pallidus interna (GPi) from Parkinson's disease brain tissue versus control brain tissue.
Keywords: NCBI GEO expression profiling by array
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Transcriptional analysis of putamen in Parkinson's disease
Post mortem tissue was dissected from two groups of age and gender matched groups of Parkinson and Control subjects
Keywords: NCBI GEO expression profiling by array
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Gene Expression Profiles in a Rabbit Model of System...
We previously reported the establishment of a rabbit (Oryctolagus cuniculus) model of Systemic Lupus Erythematosus (SLE) in which peptide immunization led to lupus-like autoantibody production including anti-Sm, -RNP, -SS-A, -SS-B and -dsDNA. Some neurological symptoms in form of seizures and nystagmus were observed. The animals used in the previous and in the present study were from a National Institute of Allergy and Infectious Diseases colony of rabbits that were pedigreed, immunoglobulin...
Keywords: NCBI GEO expression profiling by array
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Peritoneal and testicular macrophage mrna expression...
Ascending bacterial infections of the male genitourinary tract by Escherichia coli are an important cause of male infertility. Thus understanding mechanisms by which immunocompetent cells such as testicular macrophages (TM) respond to infection and how bacterial pathogens manipulate defense pathways is of great relevance. Following infection with uropathogenic E. coli (UPEC) whole genome expression profiling revealed induction of the calcium-dependent nuclear factor of activated T cells (NFAT...
Keywords: NCBI GEO macrophages expression profiling by array
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Expression data from advanced Parkinson's disease (P...
Sub-thalamic deep brain stimulation (DBS) reversibly modulates Parkinson’s disease (PD) motor symptoms, providing an unusual opportunity to compare leukocyte transcripts in the same subjects before and after neurosurgery and after disconnecting the stimulus (ON-and OFF-stimulus). Here, we report rapid stimulus-induced and largely reversible changes in PD leukocyte transcripts, which were larger in scope than the disease-induced changes. These transcript changes classified advanced pre- from p...
Keywords: NCBI GEO expression profiling by array
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Polyglutamine Atrophin provokes neurodegeneration in...
Dentatorubral-pallidoluysian Atrophy (DRPLA) is a human polyQ disease caused by the expansion of a CAG strech in the atrophin-1 (at-1) gene. In all vertebrates, a second atrophin gene (at-2) is present and it encodes a related protein void of polyQ tracks. In D.melanogaster there is one conserved Atrophin (Atro) gene, ubiquitously expressed, which contains all functional domains of vertebrate Atrophins, including two polyQ stretches. To understand to what extent transcriptional alterations ca...
Keywords: NCBI GEO expression profiling by array
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