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19 projects found
Induction of Dendritic Cell-like Phenotype in Macrop...
Foam cell formation from monocyte-derived macrophages is a hallmark of atheroscle-rotic lesions. Aspects of this process can be recapitulated in vitro by exposing MCSF-induced or platelet factor4 (CXCL4)-induced macrophages to oxidized (ox) or minimally modified (mm) low density lipoprotein (LDL). We measured gene expression in periph-eral blood mononuclear cells (PBMCs), monocytes and macrophages treated with CXCL1 (GRO-α) or CCL2 (MCP-1) as well as foam cells induced by native LDL, mmLDL or...
Keywords: PBMC monocytes macrophages foam cells chemokines macrophages expression profiling by array
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Similarities and differences in the transcriptome of...
Phenotypic and functional diversity between macrophage subpopulations reflects their plasticity to respond to microenvironmental signals. Apart from detecting differences in expression profiles, the comparison of the transcriptomes of different macrophage populations may also allow the definition of molecular similarities between these subsets.Transcriptome analysis of human Kuppfer cells, alveolar, splenic and atherosclerotic plaque residing macrophages using microarrays, identified 42 genes...
Keywords: NCBI GEO macrophages expression profiling by array
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Expression data from mouse bone marrow macrophages f...
Bone marrow macrophages were cultured from 16 week old apoE-deficient F2 mice from an AKRxDBA/2 intercrossGene expression profiling was performed using Affy 430v2 arrays, and 1967 informative SNP markers were genotyped for each mouseSupplementary file of SNP data attached below from ParAllele 5K mouse linkage panel
Keywords: Genetic-genomic macrophages expression profiling by array
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