AETIONOMY prospective study

Organising mechanistic knowledge about neurodegenerative diseases for the improvement of drug development and therapy

groups: IMI Projects

tags: IMI Translational Medicine

Data Standards Implemented: CDISC
Therapeutic Area Standards (Disease Area): -
Study Protocal Description: http://www.aetionomy.eu/content/dam/scai/AETIONOMY/Dokumente/Aetionomy_Newsletter4_web.pdf
Multi-center Study: True
Description of Cohorts: http://www.aetionomy.eu/content/dam/scai/AETIONOMY/Dokumente/Aetionomy_Newsletter4_web.pdf
Study Type: OBSERVATIONAL
Study Type Comment: -
Primary Purpose: To validate the disease taxonomies proposed by the AETIONOMY project
Study Phase: Recruitment
Intervention Model: -
Study Classification: -
Indication: -

Age Range (Low Limit) of Study: -
Age Range (Upper Limit) of Study: -
Age Unit (of the above ranges): Year
BMI Range: -
BMI Range (lower limit): -
BMI Range (upper limit): -
Informed Consent: True
Planned Arm (Description of Sub-cohorts): A) PD groups (n=325): Idiopathic PD (n=240), Genetic PD with mutation in Parkin, LRRK2 or GBA (n=40), Subject at risk of PD: first degree relatives or iRBD (n=45). B) AD groups (n=150): MCI/Prodromal AD (n=90), preclinical AD (n=60), Healthy C) Controls (n=180): 90 matching PD, 90 matching AD.