A observational study of people with mild, moderate and severe asthma including both smokers and non-smokers and a control group of healthy volunteers. An extensive range of clinical parameters and omics from blood, urine, sputum and bronchial brushings and biopsy and nasal brushings.
- Primary Purpose
- Phenotype severe asthma
- Description of Cohorts
- Cohort A adult: Severe asthma non-smoking (under 5 pack years). Cohort B Adult: Severe asthma smoking (5+ pack years). Cohort C Adult: Mild-moderate asthma. Cohort D adult: Healthy volunteers. Cohort A Paediatric: Severe school aged asthma. Cohort B Paediatric: Mild-moderate school aged asthma. Cohort C Paediatric: Severe pre-school aged asthma/wheeze. Cohort D Paediatric: Mild-moderate pre-school aged asthma/wheeze. Adult: Cohort A: 367, Cohort B: 121, Cohort C: 130, Cohort D: 112, Paediatric Cohort A: 102, Cohort B: 58, Cohort C: 83, Cohort D: 56.
- Informed Consent Given?
- Multi-center Study?
- Number of subjects
- Type of Samples Collected
- Age Range of Study Participants
- 1-79 year
- BMI Range of Study Participants