Activation of mTOR controls the loss of TCRζ in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation

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10 replicate T cell samples from SLE (Lupus) patients9 replicate T cell samples from healthy control (BC) subjects4 replicate Nitric Oxide (NOC-18) stimulated T cell samples from 4 of the control subjects4 replicate CD3/CD28 stimulated T cell samples from 4 of the control subjects

Project

Project Title: Activation of mTOR controls the loss of TCRζ in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation
Project website: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA110359

Datasets

Activation of mTOR controls the loss of TCRζ in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation

Study description

Primary Purpose: -
Description of Cohorts: -
Informed Consent Given?: -
Multi-center Study?: -

Subjects

Organisms: Homo sapiens
Number of subjects: -
Diseases: systemic lupus erythematosus
Sample Sources: -
Type of Samples Collected: -

Demographic and Participant Information