Divergent genome wide transcriptional profiles from immune cell subsets isolated from SLE patients with different ancestral backgrounds

Peripheral blood was collected from 21 African-American (AA) and 21 European-American (EA) SLE patients, 5 AA controls, and 5 EA controls. CD4+ T-cells, CD8+ T-cells, monocytes and B cells were purified by flow sorting. Each cell subset from each subject was run on an Illumina HumanHT-12 V4 expression BeadChip array (n=208 arrays).


Primary Purpose
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Description of Cohorts
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Informed Consent Given?
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Multi-center Study?
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Organisms
Homo sapiens
Number of subjects
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Diseases
systemic lupus erythematosus
Sample Sources
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Type of Samples Collected
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Age Range of Study Participants
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BMI Range of Study Participants
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