Bruton's Tyrosine Kinase Regulates TLR9 but not TLR7 Signaling in Human pDCs
pDCs from healthy donors (n=4) were treated with gardiquimod (TLR7 agonist) or ODN 2216 (TLR9 agonist) with or without BTK inhibitor for 3 hours.
- Primary Purpose
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- Description of Cohorts
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- Informed Consent Given?
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- Multi-center Study?
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- Organisms
- Homo sapiens
- Number of subjects
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- Diseases
- systemic lupus erythematosus
- Sample Sources
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- Type of Samples Collected
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