Whole genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus [metylation]

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We performed whole genome transcription and DNA methylation analysis in PBMC of 30 SLE patients, including 15 with LN (SLE LN+) and 15 without LN (SLE LN-), and 25 normal controls (NC) using HumanHT-12 Beadchips and Illumina Human Methy450 chips. The serum pro-inflammatory cytokines were quantified using Bio-plex human cytokine 27-plex assay.

Project

Project Title: Whole genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus [metylation]
Project website: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA324379

Datasets

Whole genome transcription and DNA methylation analysis of peripheral blood mononuclear cells identified aberrant gene regulation pathways in systemic lupus erythematosus [metylation]

Study description

Primary Purpose: -
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Informed Consent Given?: -
Multi-center Study?: -

Subjects

Organisms: Homo sapiens
Number of subjects: -
Diseases: systemic lupus erythematosus
Sample Sources: -
Type of Samples Collected: -

Demographic and Participant Information