The relationship between the gene expression profile in the synovium of RA patients at baseline and the clinical response to infliximab treatment
All patients were hybridized in a dual channel reference design where the reference was always labeled with cy3 and the samples with cy5. In total, RNA was extracted from synovial biopsies of 62 patients. 18 patients were good responding, 30 moderate responding and 14 non-responding. Universal Human Reference RNA from Stratagene was used as reference. All samples were amplified with the RiboAmp II kit before labeling and hybridization.
- Primary Purpose
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- Description of Cohorts
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- Informed Consent Given?
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- Multi-center Study?
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- Organisms
- Homo sapiens
- Number of subjects
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- Diseases
- rheumatoid arthritis
- Sample Sources
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- Type of Samples Collected
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