ABI-MS

Patients with MS or Clinically Isolated Syndrome (CIS) diagnosis according to McDonald criteria and who were prescribed IFN-beta-1a intramuscularly (IM), IFN-beta-1a subcutaneously (SC), or IFN-beta-1b SC (original product or biosimilar) were recruited from January 30, 2014 to January 22, 2016. Patients who were not naive to IFN-beta were excluded.


Primary Purpose
Anti-Biopharmaceutical Immunization: Prediction and analysis of clinical relevance to minimize the risk of immunization in multiple sclerosis patients on interferon-beta treatment
Study Types
observational
Description of Cohorts
147 patients (103 female, 44 male) diagnosed with MS.
Informed Consent Given?
True
Multi-center Study?
True
Organisms
Homo sapiens
Number of subjects
147
Diseases
multiple sclerosis
Sample Sources
tissue sample
Type of Samples Collected
DNA RNA PBMCs plasma