Lung biopsies from asthmatics pre- and post- steroid treatment and from healthy control
To better understand the therapeutic potential of targeting Th2 inflammation in asthma, we performed genome-wide expression profiling of endobronchial biopsies in asthmatics and healthy controls stratified according a previously defined three-gene Th2 signature in bronchial epithelium.The Th2 signature is defined as relatively high expression of POSTN, CLCA1, and SERPINB2.
keywords: NCBI GEO expression profiling by array
- Project website
- https://www.ncbi.nlm.nih.gov/bioproject/PRJNA129953
- Start date
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- End date
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- Funding
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- Types
- NCBI GEO
- Project publications
- https://pubmed.ncbi.nlm.nih.gov/21187436