Released on 2025-05-05

IL-2 Hepatotox-Data

Accession number

ELU-2-5BD76B-1

Description

In vitro assays to identify IL-2 mediated hepatotoxicity

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Project

Project Title: Immune safety avatar: nonclinical mimicking of the immune system effects of immunomodulatory therapies
Project website: https://www.imi.europa.eu/projects-results/project-factsheets/imsavar

Studies

Study title: IL-2 Hepatotox-Cohort

General Dataset Information

Version: V1.0
Created on: 2025-03-11
Updated on: 2025-03-11
Experiment types: Genetic and derived genetic data
Type of Samples Collected: Blood
Number of Samples Collected: 60

Dataset contacts

Data owner: -
Main contact: Susanne Schiffmann
Email: susanne.schiffmann@itmp.fraunhofer.de
Affiliation: Fraunhofer Institute for Translational Medicine and Pharmacology

Use restrictions

Constrained permissions

Use Restriction	Remarks	Category (GA4GH)
The coded biomaterials and medical data are stored by the Biobank for Surgical Research (BCF), but may also be shared with other institutions such as universities, research institutes, and research companies, possibly within the European Union, for more specifically defined medical research purposes under previously established rules.	Restricted type of recipients. Does the consent limit the type of recipients? E.g. data can be sent only to a specific type of institution such as private research institutions or public research institutions or to a named list of institutions.	Institution-Specific restrictions (IS)
Use of data is limited to the research project imSAVAR	Use of DATA is limited to the RESEARCH PROJECT. Is the use of data limited to the project named in the Submission sheet?	Project-Specific restrictions (PS)
Limitation to the research project includes the Research Use.	- Does the limitation to the RESEARCH PROJECT include the RESEARCH USE (as defined in the Consortium Agreement)?	Project-Specific restrictions (PS)
All beneficiaries who have signed the CA and DAS can request access to the data.	User specific restrictions Is the use limited to approved users/groups/institutions?	User-Specific restrictions (US)

Obligations

Use Restriction	Remarks	Category (GA4GH)
For Hepatocyte data, Dr. Damm (Department of Hepatobiliary Surgery and Visceral Transplantation, University Hospital, Leipzig University, Leipzig, Germany) have to be cited.	Publication requirements Are there any requirements in case of publications based on the DATA? E.g. papers should cite the cohort study.	Publication Required (PUB)

Permissions

Use Restriction	Remarks	Category (GA4GH)
There is no requirement to return data.	Data return requirements Is there a requirement to return data or documents to the database/resource?	Return data to database/resource (RTN)