whole brains from nicotinic acetylcholine receptor subunit mutant mice and littermate controls

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Studies using mice with beta4 nicotinic acetylcholine receptor (nAChR) subunit deficiency (beta4-/- mice) helped reveal the roles of this subunit in bradycardiac response to vagal stimulation, nicotine-induced seizure activity and anxiety. In order to identify genes that might be related to beta4-containing nAChRs activity, we compared the mRNA expression profiles of brains from beta4-/- and wild-type mice using Affymetrix U74Avr2 microarray.

keywords: knockout mice nicotinic acetylcholine receptor expression profiling by array

General Project Information

Project website: https://www.ncbi.nlm.nih.gov/bioproject/PRJNA96327
Start date: -
End date: -
Funding: -
Types: NCBI GEO
Project publications: https://pubmed.ncbi.nlm.nih.gov/16985005

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Studies and datasets

Study	Datasets
whole brains from nicotinic acetylcholine receptor subunit mutant mice and littermate controls	whole brains from nicotinic acetylcholine receptor subunit mutant mice and littermate controls